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ADR3, a next generation i-body to human RANKL, inhibits osteoclast formation and bone resorption

Osteoporosis is a chronic skeletal condition characterized by low bone mass and deteriorated microarchitecture of bone tissue and puts tens of millions of people at high risk of fractures. New therapeutic agents like i-bodies, a class of next-generation single-domain antibodies, are needed to overco...

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Detalles Bibliográficos
Autores principales:	Qiu, Heng, Hosking, Christopher, Rothzerg, Emel, Samantha, Ariela, Chen, Kai, Kuek, Vincent, Jin, Haiming, Zhu, Sipin, Vrielink, Alice, Lim, Kevin, Foley, Michael, Xu, Jiake
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929471/ https://www.ncbi.nlm.nih.gov/pubmed/36634847 http://dx.doi.org/10.1016/j.jbc.2023.102889

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