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SPECC1L binds the myosin phosphatase complex MYPT1/PP1β and can regulate its distribution between microtubules and filamentous actin

The subcellular localization, activity , and substrate specificity of the serine/threonine protein phosphatase 1 catalytic subunit (PP1(cat)) is mediated through its dynamic association with regulatory subunits in holoenzyme complexes. While some functional overlap is observed for the three human PP...

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Detalles Bibliográficos
Autores principales: Mehta, Virja, Decan, Nathalie, Ooi, Sarah, Gaudreau-Lapierre, Antoine, Copeland, John W., Trinkle-Mulcahy, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929477/
https://www.ncbi.nlm.nih.gov/pubmed/36634848
http://dx.doi.org/10.1016/j.jbc.2023.102893