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SPECC1L binds the myosin phosphatase complex MYPT1/PP1β and can regulate its distribution between microtubules and filamentous actin
The subcellular localization, activity , and substrate specificity of the serine/threonine protein phosphatase 1 catalytic subunit (PP1(cat)) is mediated through its dynamic association with regulatory subunits in holoenzyme complexes. While some functional overlap is observed for the three human PP...
Autores principales: | Mehta, Virja, Decan, Nathalie, Ooi, Sarah, Gaudreau-Lapierre, Antoine, Copeland, John W., Trinkle-Mulcahy, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929477/ https://www.ncbi.nlm.nih.gov/pubmed/36634848 http://dx.doi.org/10.1016/j.jbc.2023.102893 |
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