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Exosomes are involved in iron transport from human blood–brain barrier endothelial cells and are modified by endothelial cell iron status

Iron is essential for normal brain development and function. Hence, understanding the mechanisms of iron efflux at the blood–brain barrier and their regulation are critical for the establishment of brain iron homeostasis. Here, we have investigated the role of exosomes in mediating the transfer of H...

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Detalles Bibliográficos
Autores principales: Palsa, Kondaiah, Baringer, Stephanie L., Shenoy, Ganesh, Spiegelman, Vladimir S., Simpson, Ian A., Connor, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929479/
https://www.ncbi.nlm.nih.gov/pubmed/36603765
http://dx.doi.org/10.1016/j.jbc.2022.102868