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Estimation of Neutral Mutation Rates and Quantification of Somatic Variant Selection Using cancereffectsizeR

Somatic nucleotide mutations can contribute to cancer cell survival, proliferation, and pathogenesis. Although research has focused on identifying which mutations are “drivers” versus “passengers," quantifying the proliferative effects of specific variants within clinically relevant contexts co...

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Detalles Bibliográficos
Autores principales: Mandell, Jeffrey D., Cannataro, Vincent L., Townsend, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929515/
https://www.ncbi.nlm.nih.gov/pubmed/36469362
http://dx.doi.org/10.1158/0008-5472.CAN-22-1508