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Improved efficacy of mesenchymal stromal cells stably expressing CXCR4 and IL-10 in a xenogeneic graft versus host disease mouse model

Previous clinical trials have shown that mesenchymal stromal cells (MSCs) can modulate graft versus host disease (GvHD) after allogeneic hematopoietic transplantation, although with variable efficacy. To improve the anti-GvHD effect of these cells, adipose tissue derived-human MSCs (Ad-MSCs) were tr...

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Detalles Bibliográficos
Autores principales: Hervás-Salcedo, Rosario, Fernández-García, María, Hernando-Rodríguez, Miriam, Suárez-Cabrera, Cristian, Bueren, Juan A., Yáñez, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929539/
https://www.ncbi.nlm.nih.gov/pubmed/36817457
http://dx.doi.org/10.3389/fimmu.2023.1062086