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Local irradiation of patient-derived tumors in immunodeficient mice

Severe combined immunodeficient mice are typically used for xenografting experiments and show reliable tumor engraftment; however, their Prkd(scid) mutation renders them highly sensitive to irradiation. Here, we describe a protocol that allows safe local irradiation of tumor xenografts in immunodefi...

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Detalles Bibliográficos
Autores principales: van der Zalm, Amber P., Bootsma, Sanne, Rodermond, Hans M., Oei, Arlene L., Bijlsma, Maarten F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929630/
https://www.ncbi.nlm.nih.gov/pubmed/36825807
http://dx.doi.org/10.1016/j.xpro.2023.102098