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Local irradiation of patient-derived tumors in immunodeficient mice
Severe combined immunodeficient mice are typically used for xenografting experiments and show reliable tumor engraftment; however, their Prkd(scid) mutation renders them highly sensitive to irradiation. Here, we describe a protocol that allows safe local irradiation of tumor xenografts in immunodefi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929630/ https://www.ncbi.nlm.nih.gov/pubmed/36825807 http://dx.doi.org/10.1016/j.xpro.2023.102098 |