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A critical period of prehearing spontaneous Ca(2+) spiking is required for hair‐bundle maintenance in inner hair cells

Sensory‐independent Ca(2+) spiking regulates the development of mammalian sensory systems. In the immature cochlea, inner hair cells (IHCs) fire spontaneous Ca(2+) action potentials (APs) that are generated either intrinsically or by intercellular Ca(2+) waves in the nonsensory cells. The extent to...

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Detalles Bibliográficos
Autores principales: Carlton, Adam J, Jeng, Jing‐Yi, Grandi, Fiorella C, De Faveri, Francesca, Ceriani, Federico, De Tomasi, Lara, Underhill, Anna, Johnson, Stuart L, Legan, Kevin P, Kros, Corné J, Richardson, Guy P, Mustapha, Mirna, Marcotti, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929643/
https://www.ncbi.nlm.nih.gov/pubmed/36594367
http://dx.doi.org/10.15252/embj.2022112118