Cargando…

Targeting HER3 for cancer treatment: a new horizon for an old target

Human epidermal growth factor receptor 3 (HER3) is a member of the human epidermal growth factor receptors family, having as its main ligands neuregulins 1 and 2. Although its poor tyrosine kinase activity entails a weak oncogenic power on its own, HER3 can heterodimerize with HER2 and/or epidermal...

Descripción completa

Detalles Bibliográficos
Autores principales: Uliano, J., Corvaja, C., Curigliano, G., Tarantino, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929675/
https://www.ncbi.nlm.nih.gov/pubmed/36764093
http://dx.doi.org/10.1016/j.esmoop.2023.100790