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Metabotropic glutamate receptor-8 relieves neonatal maternal separation-induced visceral hypersensitivity in rats by regulating expression of TNF-α

BACKGROUND: Visceral hypersensitivity (VH) is one of the most common causes of irritable bowel syndrome (IBS). The anti-hyperalgesic effects of metabotropic glutamate receptor 8 (mGluR8) has been identified in the central nervous system (CNS). However, whether this receptor has a similar function in...

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Detalles Bibliográficos
Autores principales: Wang, Xiaobo, Shao, Limei, Hua, Hongjun, Chen, Yanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929757/
https://www.ncbi.nlm.nih.gov/pubmed/36819583
http://dx.doi.org/10.21037/atm-22-6452