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Peroxiredoxin 6 alleviates high glucose-induced inflammation and apoptosis in HK-2 cells by inhibiting TLR4/NF-κB signaling

BACKGROUND: This research sought to elucidate the effects of peroxiredoxin 6 (PRDX6) on the biological processes in diabetic nephropathy (DN) and to identify the underlying regulatory mechanism related to toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) signaling. METHODS: To induce an in...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Wu, Rong, Liu, Tianxi, Ma, Hongbin, Xue, Guozhong, Liu, Minglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929773/
https://www.ncbi.nlm.nih.gov/pubmed/36819569
http://dx.doi.org/10.21037/atm-22-6063