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Pharmacokinetics and bioequivalence study of montelukast sodium oral soluble film and chewable tablet in healthy Chinese volunteers: randomized trials under fasting and fed conditions

BACKGROUND: The oral soluble film (OSF) is a new drug delivery system. Whether montelukast sodium OSF has similar pharmacokinetic (PK) properties and bioequivalence to chewable tablet (CT) should be investigated. METHODS: This study, conducted at Haikou People’s Hospital, consisted of two trials: a...

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Detalles Bibliográficos
Autores principales: Zhu, Gangzhi, Wang, Liu, Han, Shengnan, Peng, Hui, Tong, Mei, Gu, Xingli, Hu, Haixun, Wang, Yue, Lv, Zhaoguo, He, Xiaoai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929805/
https://www.ncbi.nlm.nih.gov/pubmed/36819512
http://dx.doi.org/10.21037/atm-22-6485