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TRPV6 deficiency attenuates stress and corticosterone-mediated exacerbation of alcohol-induced gut barrier dysfunction and systemic inflammation

INTRODUCTION: Chronic stress is co-morbid with alcohol use disorder that feedback on one another, thus impeding recovery from both disorders. Stress and the stress hormone corticosterone aggravate alcohol-induced intestinal permeability and liver damage. However, the mechanisms involved in compoundi...

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Detalles Bibliográficos
Autores principales: Meena, Avtar S., Shukla, Pradeep K., Rao, Rupa, Canelas, Cherie, Pierre, Joseph F., Rao, RadhaKrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929865/
https://www.ncbi.nlm.nih.gov/pubmed/36817471
http://dx.doi.org/10.3389/fimmu.2023.1093584