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Differential haplotype expression in class I MHC genes during SARS-CoV-2 infection of human lung cell lines

INTRODUCTION: Cell entry of SARS-CoV-2 causes genome-wide disruption of the transcriptional profiles of genes and biological pathways involved in the pathogenesis of COVID-19. Expression allelic imbalance is characterized by a deviation from the Mendelian expected 1:1 expression ratio and is an impo...

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Detalles Bibliográficos
Autores principales: Francisco Junior, Ronaldo da Silva, Temerozo, Jairo R., Ferreira, Cristina dos Santos, Martins, Yasmmin, Souza, Thiago Moreno L., Medina-Acosta, Enrique, de Vasconcelos, Ana Tereza Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929942/
https://www.ncbi.nlm.nih.gov/pubmed/36818472
http://dx.doi.org/10.3389/fimmu.2022.1101526