Exploration of a Large Virtual Chemical Space: Identification of Potent Inhibitors of Lactate Dehydrogenase-A against Pancreatic Cancer

[Image: see text] It is imperative to explore the gigantic available chemical space to identify new scaffolds for drug lead discovery. Identifying potent hits from virtual screening of large chemical databases is challenging and computationally demanding. Rather than the traditional two-dimensional...

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Detalles Bibliográficos
Autores principales: Sharma, Horrick, Sharma, Pragya, Urquiza, Uzziah, Chastain, Lerin R., Ihnat, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930117/
https://www.ncbi.nlm.nih.gov/pubmed/36646658
http://dx.doi.org/10.1021/acs.jcim.2c01544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930117/
https://www.ncbi.nlm.nih.gov/pubmed/36646658
http://dx.doi.org/10.1021/acs.jcim.2c01544

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