Cargando…
Accurate Prediction of Enzyme Thermostabilization with Rosetta Using AlphaFold Ensembles
[Image: see text] Thermostability enhancement is a fundamental aspect of protein engineering as a biocatalyst’s half-life is key for its industrial and biotechnological application, particularly at high temperatures and under harsh conditions. Thermostability changes upon mutation originate from mod...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930118/ https://www.ncbi.nlm.nih.gov/pubmed/36647575 http://dx.doi.org/10.1021/acs.jcim.2c01083 |