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Accurate Prediction of Enzyme Thermostabilization with Rosetta Using AlphaFold Ensembles
[Image: see text] Thermostability enhancement is a fundamental aspect of protein engineering as a biocatalyst’s half-life is key for its industrial and biotechnological application, particularly at high temperatures and under harsh conditions. Thermostability changes upon mutation originate from mod...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930118/ https://www.ncbi.nlm.nih.gov/pubmed/36647575 http://dx.doi.org/10.1021/acs.jcim.2c01083 |