Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure

Hepatocytes grow their apical surfaces anisotropically to generate a 3D network of bile canaliculi (BC). BC elongation is ensured by apical bulkheads, membrane extensions that traverse the lumen and connect juxtaposed hepatocytes. We hypothesize that apical bulkheads are mechanical elements that sha...

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Detalles Bibliográficos
Autores principales: Bebelman, Maarten P., Bovyn, Matthew J., Mayer, Carlotta M., Delpierre, Julien, Naumann, Ronald, Martins, Nuno P., Honigmann, Alf, Kalaidzidis, Yannis, Haas, Pierre A., Zerial, Marino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930133/
https://www.ncbi.nlm.nih.gov/pubmed/36716168
http://dx.doi.org/10.1083/jcb.202208002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930133/
https://www.ncbi.nlm.nih.gov/pubmed/36716168
http://dx.doi.org/10.1083/jcb.202208002

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