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Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure
Hepatocytes grow their apical surfaces anisotropically to generate a 3D network of bile canaliculi (BC). BC elongation is ensured by apical bulkheads, membrane extensions that traverse the lumen and connect juxtaposed hepatocytes. We hypothesize that apical bulkheads are mechanical elements that sha...
Autores principales: | Bebelman, Maarten P., Bovyn, Matthew J., Mayer, Carlotta M., Delpierre, Julien, Naumann, Ronald, Martins, Nuno P., Honigmann, Alf, Kalaidzidis, Yannis, Haas, Pierre A., Zerial, Marino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930133/ https://www.ncbi.nlm.nih.gov/pubmed/36716168 http://dx.doi.org/10.1083/jcb.202208002 |
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