Validation of automated positive cell and region detection of immunohistochemically stained laryngeal tumor tissue using digital image analysis

OBJECTIVES: This study aimed to validate a digital image analysis (DIA) workflow for automatic positive cell detection and positive region delineation for immunohistochemical hypoxia markers with a nuclear (hypoxia-inducible factor 1α [HIF-1α]) and a cytoplasmic (pimonidazole [PIMO]) staining patter...

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Detalles Bibliográficos
Autores principales: Smits, Hilde J.G., Swartz, Justin E., Philippens, Marielle E.P., de Bree, Remco, Kaanders, Johannes H.A.M., Koppes, Sjors A., Breimer, Gerben E., Willems, Stefan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930147/
https://www.ncbi.nlm.nih.gov/pubmed/36818021
http://dx.doi.org/10.1016/j.jpi.2023.100198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930147/
https://www.ncbi.nlm.nih.gov/pubmed/36818021
http://dx.doi.org/10.1016/j.jpi.2023.100198

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