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Validation of automated positive cell and region detection of immunohistochemically stained laryngeal tumor tissue using digital image analysis

OBJECTIVES: This study aimed to validate a digital image analysis (DIA) workflow for automatic positive cell detection and positive region delineation for immunohistochemical hypoxia markers with a nuclear (hypoxia-inducible factor 1α [HIF-1α]) and a cytoplasmic (pimonidazole [PIMO]) staining patter...

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Detalles Bibliográficos
Autores principales:	Smits, Hilde J.G., Swartz, Justin E., Philippens, Marielle E.P., de Bree, Remco, Kaanders, Johannes H.A.M., Koppes, Sjors A., Breimer, Gerben E., Willems, Stefan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930147/ https://www.ncbi.nlm.nih.gov/pubmed/36818021 http://dx.doi.org/10.1016/j.jpi.2023.100198

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