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Apo-metallothionein-3 cooperatively forms tightly compact structures under physiological conditions

Metallothioneins (MTs) are essential mammalian metal chaperones. MT isoform 1 (MT1) is expressed in the kidneys and isoform 3 (MT3) is expressed in nervous tissue. For MTs, the solution-based NMR structure was determined for metal-bound MT1 and MT2, and only one X-ray diffraction structure on a crys...

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Detalles Bibliográficos
Autores principales: Yuan, Amelia T., Korkola, Natalie C., Stillman, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930159/
https://www.ncbi.nlm.nih.gov/pubmed/36639030
http://dx.doi.org/10.1016/j.jbc.2023.102899