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STING trafficking as a new dimension of immune signaling

The cGAS–STING pathway is an evolutionarily conserved immune signaling pathway critical for microbial defense. Unlike other innate immune pathways that largely rely on stationary cascades of signaling events, STING is highly mobile in the cell. STING is activated on the ER, but only signals after it...

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Detalles Bibliográficos
Autores principales: Jeltema, Devon, Abbott, Kennady, Yan, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930166/
https://www.ncbi.nlm.nih.gov/pubmed/36705629
http://dx.doi.org/10.1084/jem.20220990