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STING trafficking as a new dimension of immune signaling
The cGAS–STING pathway is an evolutionarily conserved immune signaling pathway critical for microbial defense. Unlike other innate immune pathways that largely rely on stationary cascades of signaling events, STING is highly mobile in the cell. STING is activated on the ER, but only signals after it...
Autores principales: | Jeltema, Devon, Abbott, Kennady, Yan, Nan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930166/ https://www.ncbi.nlm.nih.gov/pubmed/36705629 http://dx.doi.org/10.1084/jem.20220990 |
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