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Epithelial senescence in idiopathic pulmonary fibrosis is propagated by small extracellular vesicles

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects 3 million people worldwide. Senescence and small extracellular vesicles (sEVs) have been implicated in the pathogenesis of IPF, although how sEVs promote disease remains unclear. Here, we profile sEVs from bronchi...

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Detalles Bibliográficos
Autores principales: Asghar, Sabha, Monkley, Susan, Smith, David J. F., Hewitt, Richard J., Grime, Ken, Murray, Lynne A., Overed-Sayer, Catherine L., Molyneaux, Philip L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930250/
https://www.ncbi.nlm.nih.gov/pubmed/36788603
http://dx.doi.org/10.1186/s12931-023-02333-5