Cargando…
Epithelial senescence in idiopathic pulmonary fibrosis is propagated by small extracellular vesicles
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects 3 million people worldwide. Senescence and small extracellular vesicles (sEVs) have been implicated in the pathogenesis of IPF, although how sEVs promote disease remains unclear. Here, we profile sEVs from bronchi...
Autores principales: | Asghar, Sabha, Monkley, Susan, Smith, David J. F., Hewitt, Richard J., Grime, Ken, Murray, Lynne A., Overed-Sayer, Catherine L., Molyneaux, Philip L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930250/ https://www.ncbi.nlm.nih.gov/pubmed/36788603 http://dx.doi.org/10.1186/s12931-023-02333-5 |
Ejemplares similares
-
Increased expression and accumulation of GDF15 in IPF extracellular matrix contribute to fibrosis
por: Radwanska, Agata, et al.
Publicado: (2022) -
Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF
por: Monkley, Susan, et al.
Publicado: (2021) -
Extracellular Vesicles: Bidirectional Accelerators of Cellular Senescence in Fibrosis?
por: Goliwas, Kayla F., et al.
Publicado: (2020) -
Modeling fibrotic alveolar transitional cells with pluripotent stem cell-derived alveolar organoids
por: Ptasinski, Victoria, et al.
Publicado: (2023) -
Extracellular vesicles in idiopathic pulmonary fibrosis: pathogenesis and therapeutics
por: Fujita, Yu
Publicado: (2022)