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Inhaled amikacin for pneumonia treatment and dissemination prevention: an experimental model of severe monolateral Pseudomonas aeruginosa pneumonia

BACKGROUND: Pseudomonas aeruginosa pneumonia is commonly treated with systemic antibiotics to ensure adequate treatment of multidrug resistant (MDR) bacteria. However, intravenous (IV) antibiotics often achieve suboptimal pulmonary concentrations. We therefore aimed to evaluate the effect of inhaled...

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Detalles Bibliográficos
Autores principales: Motos, Ana, Yang, Hua, Li Bassi, Gianluigi, Yang, Minlan, Meli, Andrea, Battaglini, Denise, Cabrera, Roberto, Bobi, Joaquim, Pagliara, Francesco, Frigola, Gerard, Camprubí-Rimblas, Marta, Fernández-Barat, Laia, Rigol, Montserrat, Ferrer-Segarra, Antoni, Kiarostami, Kasra, Martinez, Daniel, Nicolau, David P., Artigas, Antonio, Pelosi, Paolo, Vila, Jordi, Torres, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930251/
https://www.ncbi.nlm.nih.gov/pubmed/36788582
http://dx.doi.org/10.1186/s13054-023-04331-x