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Regulon active landscape reveals cell development and functional state changes of human primary osteoblasts in vivo

BACKGROUND: While transcription factor (TF) regulation is known to play an important role in osteoblast development, differentiation, and bone metabolism, the molecular features of TFs in human osteoblasts at the single-cell resolution level have not yet been characterized. Here, we identified modul...

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Detalles Bibliográficos
Autores principales: Wang, Shengran, Gong, Yun, Wang, Zun, Meng, Xianghe, Luo, Zhe, Papasian, Christopher J., Greenbaum, Jonathan, Li, Yisu, Liang, Qilan, Chen, Yiping, Li, Xiaohua, Xiang, Qiu, Zhang, Hiuxi, Liu, Ying, Cheng, Liang, Hu, Yihe, Tan, Lijun, Shen, Hui, Xiao, Hongmei, Deng, Hongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930257/
https://www.ncbi.nlm.nih.gov/pubmed/36793138
http://dx.doi.org/10.1186/s40246-022-00448-2