GLIS3 regulates transcription of thyroid hormone biosynthetic genes in coordination with other thyroid transcription factors

BACKGROUND: Loss of the transcription factor GLI-Similar 3 (GLIS3) function causes congenital hypothyroidism (CH) in both humans and mice due to decreased expression of several thyroid hormone (TH) biosynthetic genes in thyroid follicular cells. Whether and to what extent, GLIS3 regulates thyroid ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Hong Soon, Grimm, Sara A., Jothi, Raja, Santisteban, Pilar, Jetten, Anton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930322/
https://www.ncbi.nlm.nih.gov/pubmed/36793061
http://dx.doi.org/10.1186/s13578-023-00979-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930322/
https://www.ncbi.nlm.nih.gov/pubmed/36793061
http://dx.doi.org/10.1186/s13578-023-00979-8

Ejemplares similares