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The 5′UTR of HCoV-OC43 adopts a topologically constrained structure to intrinsically repress translation

The emergence of SARS-CoV-2, which is responsible for the COVID-19 pandemic, has highlighted the need for rapid characterization of viral mechanisms associated with cellular pathogenesis. Viral UTRs represent conserved genomic elements that contribute to such mechanisms. Structural details of most C...

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Detalles Bibliográficos
Autores principales: Mackeown, Matthew, Kung, Yu-An, Davila-Calderon, Jesse, Ford, William P., Luo, Le, Henry, Barrington, Li, Mei-Ling, Brewer, Gary, Shih, Shin-Ru, Tolbert, Blanton S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930382/
https://www.ncbi.nlm.nih.gov/pubmed/36805339
http://dx.doi.org/10.1016/j.jbc.2023.103028