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Protein biomarkers for response to XPO1 inhibition in haematologic malignancies

XPO1 (Exportin‐1) is the nuclear export protein responsible for the normal shuttling of several proteins and RNA species between the nucleocytoplasmic compartment of eukaryotic cells. XPO1 recognizes the nuclear export signal (NES) of its cargo proteins to facilitate its export. Alterations of nucle...

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Detalles Bibliográficos
Autores principales: Totiger, Tulasigeri M., Chaudhry, Sana, Musi, Elgilda, Afaghani, Jumana, Montoya, Skye, Owusu‐Ansah, Frank, Lee, Stanley, Schwartz, Gary, Klimek, Virginia, Taylor, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930413/
https://www.ncbi.nlm.nih.gov/pubmed/36722323
http://dx.doi.org/10.1111/jcmm.17667