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Protein biomarkers for response to XPO1 inhibition in haematologic malignancies
XPO1 (Exportin‐1) is the nuclear export protein responsible for the normal shuttling of several proteins and RNA species between the nucleocytoplasmic compartment of eukaryotic cells. XPO1 recognizes the nuclear export signal (NES) of its cargo proteins to facilitate its export. Alterations of nucle...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930413/ https://www.ncbi.nlm.nih.gov/pubmed/36722323 http://dx.doi.org/10.1111/jcmm.17667 |