Downregulation of SF3B2 protects CNS neurons in models of multiple sclerosis

OBJECTIVE: Neurodegeneration induced by inflammatory stress in multiple sclerosis (MS) leads to long‐term neurological disabilities that are not amenable to current immunomodulatory therapies. METHODS AND RESULTS: Here, we report that neuronal downregulation of Splicing factor 3b subunit 2 (SF3B2),...

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Detalles Bibliográficos
Autores principales: Jeong, Ye Eun, Rajbhandari, Labchan, Kim, Byung Woo, Venkatesan, Arun, Hoke, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930435/
https://www.ncbi.nlm.nih.gov/pubmed/36574260
http://dx.doi.org/10.1002/acn3.51717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930435/
https://www.ncbi.nlm.nih.gov/pubmed/36574260
http://dx.doi.org/10.1002/acn3.51717

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