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Ras-mediated activation of mTORC2 promotes breast epithelial cell migration and invasion

We previously identified the mechanistic target of rapamycin complex 2 (mTORC2) as an effector of Ras for the control of directed cell migration in Dictyostelium. Recently, the Ras-mediated regulation of mTORC2 was found to be conserved in mammalian cells, and mTORC2 was shown to be an effector of o...

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Detalles Bibliográficos
Autores principales: Collins, Shannon E., Wiegand, Mollie E., Werner, Alyssa N., Brown, Isabella N., Mundo, Mary I., Swango, Douglas J., Mouneimne, Ghassan, Charest, Pascale G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930525/
https://www.ncbi.nlm.nih.gov/pubmed/36542482
http://dx.doi.org/10.1091/mbc.E22-06-0236