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GLIS1 intervention enhances anti-PD1 therapy for hepatocellular carcinoma by targeting SGK1-STAT3-PD1 pathway

BACKGROUND: GLI-similar 1 (GLIS1) is one of of Krüppel-like zinc finger proteins, which are either stimulators or inhibitors of genetic transcription. Nevertheless, its effects on T cell were elusive. METHODS: In this study, we intend to explore the effects of GLIS1 on modulating the anticancer pote...

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Detalles Bibliográficos
Autores principales: Rong, Dawei, Wang, Yuliang, Liu, Li, Cao, Hengsong, Huang, Tian, Liu, Hanyuan, Hao, Xiaopei, Sun, Guangshun, Sun, Guoqiang, Zheng, Zhiying, Kang, Junwei, Xia, Yongxiang, Chen, Ziyi, Tang, Weiwei, Wang, Xuehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930610/
https://www.ncbi.nlm.nih.gov/pubmed/36787938
http://dx.doi.org/10.1136/jitc-2022-005126