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Elevated amyloid beta disrupts the nanoscale organization and function of synaptic vesicle pools in hippocampal neurons
Alzheimer’s disease is linked to increased levels of amyloid beta (Aβ) in the brain, but the mechanisms underlying neuronal dysfunction and neurodegeneration remain enigmatic. Here, we investigate whether organizational characteristics of functional presynaptic vesicle pools, key determinants of inf...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930632/ https://www.ncbi.nlm.nih.gov/pubmed/35368053 http://dx.doi.org/10.1093/cercor/bhac134 |