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Endotoxin tolerance and low activation of TLR-4/NF-κB axis in monocytes of COVID-19 patients

ABSTRACT: Higher endotoxin in the circulation may indicate a compromised state of host immune response against coinfections in severe COVID-19 patients. We evaluated the inflammatory response of monocytes from COVID-19 patients after lipopolysaccharide (LPS) challenge. Whole blood samples of healthy...

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Detalles Bibliográficos
Autores principales: Dorneles, Gilson P., Teixeira, Paula C., Peres, Alessandra, Rodrigues Júnior, Luiz Carlos, da Fonseca, Simone Gonçalves, Monteiro, Marta Chagas, Eller, Sarah, Oliveira, Tiago F., Wendland, Eliana M., Romão, Pedro R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930695/
https://www.ncbi.nlm.nih.gov/pubmed/36790534
http://dx.doi.org/10.1007/s00109-023-02283-x