Cargando…

Endotoxin tolerance and low activation of TLR-4/NF-κB axis in monocytes of COVID-19 patients

ABSTRACT: Higher endotoxin in the circulation may indicate a compromised state of host immune response against coinfections in severe COVID-19 patients. We evaluated the inflammatory response of monocytes from COVID-19 patients after lipopolysaccharide (LPS) challenge. Whole blood samples of healthy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dorneles, Gilson P., Teixeira, Paula C., Peres, Alessandra, Rodrigues Júnior, Luiz Carlos, da Fonseca, Simone Gonçalves, Monteiro, Marta Chagas, Eller, Sarah, Oliveira, Tiago F., Wendland, Eliana M., Romão, Pedro R. T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930695/ https://www.ncbi.nlm.nih.gov/pubmed/36790534 http://dx.doi.org/10.1007/s00109-023-02283-x

Ejemplares similares

Viral load is associated with mitochondrial dysfunction and altered monocyte phenotype in acute severe SARS-CoV-2 infection
por: Romão, Pedro RT, et al.
Publicado: (2022)

Increased LPS levels coexist with systemic inflammation and result in monocyte activation in severe COVID-19 patients
por: Teixeira, Paula C., et al.
Publicado: (2021)

Expression of TLR4-MyD88 and NF-κB in the Iris during Endotoxin-Induced Uveitis
por: Li, Shang, et al.
Publicado: (2010)

Immunoregulation induced by autologous serum collected after acute exercise in obese men: a randomized cross-over trial
por: Dorneles, Gilson P., et al.
Publicado: (2020)

NF-κB-DICER-miRs Axis Regulates TNF-α Expression in Responses to Endotoxin Stress
por: Guan, Yi, et al.
Publicado: (2015)

NF-κB inhibition attenuates LPS-induced TLR4 activation in monocyte cells
por: Wan, Jian, et al.
Publicado: (2016)

Paeonol protects endotoxin-induced acute kidney injury: potential mechanism of inhibiting TLR4-NF-κB signal pathway
por: Fan, Hua-Ying, et al.
Publicado: (2016)

Sustained Immunoparalysis in Endotoxin-Tolerized Monocytic Cells
por: Weisheit, Christina K., et al.
Publicado: (2020)

TLR2 Ligands Induce NF-κB Activation from Endosomal Compartments of Human Monocytes
por: Brandt, Karim J., et al.
Publicado: (2013)

Extracts of Salvia-Nelumbinis Naturalis Ameliorate Nonalcoholic Steatohepatitis via Inhibiting Gut-Derived Endotoxin Mediated TLR4/NF-κB Activation
por: Shu, Xiangbing, et al.
Publicado: (2017)

Potential Anticarcinogenic Effects From Plasma of Older Adults After Exercise Training: An Exploratory Study
por: Peres, Alessandra, et al.
Publicado: (2022)

Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-κB-dependent activation of the urokinase plasminogen activator system
por: Killeen, S D, et al.
Publicado: (2009)

The TLR-NF-kB axis contributes to the monocytic inflammatory response against a virulent strain of Lichtheimia corymbifera, a causative agent of invasive mucormycosis
por: Montaño, Dolly E., et al.
Publicado: (2022)

The monocyte activation test detects potentiated cytokine release resulting from the synergistic effect of endotoxin and non-endotoxin pyrogens
por: Solati, Shabnam, et al.
Publicado: (2022)

Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner
por: Xie, Mengru, et al.
Publicado: (2020)

Endotoxin enhances the fibrinolytic activity of monocytes incorporated in a fibrin clot
por: Grosjean, A, et al.
Publicado: (2005)

A System Dynamics Model to Predict the Human Monocyte Response to Endotoxins
por: Álvarez, Enrique, et al.
Publicado: (2017)

Pregnancy tailors endotoxin-induced monocyte and neutrophil responses in the maternal circulation
por: Farias-Jofre, Marcelo, et al.
Publicado: (2022)

ATP128 Clinical Therapeutic Cancer Vaccine Activates NF-κB and IRF3 Pathways through TLR4 and TLR2 in Human Monocytes and Dendritic Cells
por: Pascolutti, Roberta, et al.
Publicado: (2022)

The ASCIZ-DYNLL1 Axis Is Essential for TLR4-Mediated Antibody Responses and NF-κB Pathway Activation
por: Liu, Rui, et al.
Publicado: (2021)

TLR7 promotes skin inflammation via activating NFκB-mTORC1 axis in rosacea
por: Huang, Yaqun, et al.
Publicado: (2023)

Acute Strenuous Exercise Induces an Imbalance on Histone H4 Acetylation/Histone Deacetylase 2 and Increases the Proinflammatory Profile of PBMC of Obese Individuals
por: Dorneles, Gilson P., et al.
Publicado: (2017)

Effects of epinephrine and norepinephrine on endotoxin-induced tissue factor expression in blood monocytes
por: de Rossi, L, et al.
Publicado: (2000)

Monocytes from Depressed Patients Display an Altered Pattern of Response to Endotoxin Challenge
por: Lisi, Lucia, et al.
Publicado: (2013)

Endotoxin-Induced Monocytic Microparticles Have Contrasting Effects on Endothelial Inflammatory Responses
por: Wen, Beryl, et al.
Publicado: (2014)

Hyper-Inflammatory Monocyte Activation Following Endotoxin Exposure in Food Allergic Infants
por: Neeland, Melanie R., et al.
Publicado: (2020)

Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities
por: Yu, Chen, et al.
Publicado: (2015)

Carbon Monoxide Blocks Lipopolysaccharide-Induced Gene Expression by Interfering with Proximal TLR4 to NF-κB Signal Transduction in Human Monocytes
por: Chhikara, Maneesha, et al.
Publicado: (2009)

New Insights into the Pivotal Role of Iron/Heme Metabolism in TLR4/NF-κB Signaling-Mediated Inflammatory Responses in Human Monocytes
por: Kang, Dong Young, et al.
Publicado: (2021)

Identification of the HSPB4/TLR2/NF-κB axis in macrophage as a therapeutic target for sterile inflammation of the cornea
por: Oh, Joo Youn, et al.
Publicado: (2012)

Metformin Attenuates Ischemia-reperfusion Injury of Fatty Liver in Rats Through Inhibition of the TLR4/NF-κB Axis
por: Li, Xiaohua, et al.
Publicado: (2020)

Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis
por: Qu, Yifan, et al.
Publicado: (2021)

Nephropathogenic Infectious Bronchitis Virus Mediates Kidney Injury in Chickens via the TLR7/NF-κB Signaling Axis
por: Li, Ning, et al.
Publicado: (2022)

Mitochondrial DNA induces nucleus pulposus cell pyroptosis via the TLR9-NF-κB-NLRP3 axis
por: Lu, Peng, et al.
Publicado: (2023)

Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling
por: Sandor, Frantisek, et al.
Publicado: (2003)

Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)
por: Qureshi, Salman T., et al.
Publicado: (1999)

TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis
por: Abdelsalam, Hadeer M., et al.
Publicado: (2022)

FFAR2 antagonizes TLR2- and TLR3-induced lung cancer progression via the inhibition of AMPK-TAK1 signaling axis for the activation of NF-κB
por: Kim, Mi-Jeong, et al.
Publicado: (2023)

Curcumin prevents high-fat diet-induced hepatic steatosis in ApoE(−/−) mice by improving intestinal barrier function and reducing endotoxin and liver TLR4/NF-κB inflammation
por: Feng, Dan, et al.
Publicado: (2019)

Combination therapy of Ulinastatin with Thrombomodulin alleviates endotoxin (LPS) - induced liver and kidney injury via inhibiting apoptosis, oxidative stress and HMGB1/TLR4/NF-κB pathway
por: Zhang, Xiong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3u8l3c1q3ma1c0cd5hcuhpr59f