Results From a Randomized, Open-Label, Crossover Study Evaluating the Effect of the Aldosterone Synthase Inhibitor Baxdrostat on the Pharmacokinetics of Metformin in Healthy Human Subjects

BACKGROUND: Due to the high comorbidity of diabetes and hypertension, co-administration of metformin with anti-hypertensive drugs is likely. Baxdrostat is an aldosterone synthase inhibitor in development for the potential treatment of hypertension. In vitro data indicated that baxdrostat inhibits th...

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Detalles Bibliográficos
Autores principales: Freeman, Mason W., Bond, Mary, Murphy, Brian, Hui, James, Isaacsohn, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930700/
https://www.ncbi.nlm.nih.gov/pubmed/36790596
http://dx.doi.org/10.1007/s40256-023-00572-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930700/
https://www.ncbi.nlm.nih.gov/pubmed/36790596
http://dx.doi.org/10.1007/s40256-023-00572-x

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