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Exploration of the mechanism of NORAD activation of TGF-β1/Smad3 through miR-136-5p and promotion of tacrolimus-induced renal fibrosis

BACKGROUND: Tacrolimus is a potent immunosuppressant, but has various side effects, with nephrotoxicity being the most common. Renal fibrosis is an important process of tacrolimus nephrotoxicity. Therefore, it is important to identify the factors that contribute to renal fibrosis after tacrolimus ne...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Guo, Jia, Pang, Xin-lu, Shang, Wen-jun, Wang, Zhi-gang, Wang, Jun-xiang, Yang, Xian-lei, Feng, Gui-wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930837/
https://www.ncbi.nlm.nih.gov/pubmed/36748746
http://dx.doi.org/10.1080/0886022X.2022.2147083