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Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator

INTRODUCTION: Type 1 diabetes, a disorder caused by autoimmune destruction of pancreatic insulin-producing cells, is more difficult to manage when it presents at a younger age. We sought to identify genetic correlates of the age of onset by conducting the first genome-wide association study (GWAS) t...

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Detalles Bibliográficos
Autores principales: Cardinale, Christopher J., Chang, Xiao, Wei, Zhi, Qu, Hui-Qi, Bradfield, Jonathan P., Polychronakos, Constantin, Hakonarson, Hakon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930890/
https://www.ncbi.nlm.nih.gov/pubmed/36817429
http://dx.doi.org/10.3389/fimmu.2023.1101488