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Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator

INTRODUCTION: Type 1 diabetes, a disorder caused by autoimmune destruction of pancreatic insulin-producing cells, is more difficult to manage when it presents at a younger age. We sought to identify genetic correlates of the age of onset by conducting the first genome-wide association study (GWAS) t...

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Detalles Bibliográficos
Autores principales:	Cardinale, Christopher J., Chang, Xiao, Wei, Zhi, Qu, Hui-Qi, Bradfield, Jonathan P., Polychronakos, Constantin, Hakonarson, Hakon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930890/ https://www.ncbi.nlm.nih.gov/pubmed/36817429 http://dx.doi.org/10.3389/fimmu.2023.1101488

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