Considering strategies for SNP selection in genetic and polygenic risk scores

Genetic risk scores (GRS) and polygenic risk scores (PRS) are weighted sums of, respectively, several or many genetic variant indicator variables. Although they are being increasingly proposed for clinical use, the best ways to construct them are still actively debated. In this commentary, we presen...

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Detalles Bibliográficos
Autores principales: St.-Pierre, Julien, Zhang, Xinyi, Lu, Tianyuan, Jiang, Lai, Loffree, Xavier, Wang, Linbo, Bhatnagar, Sahir, Greenwood, Celia M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930898/
https://www.ncbi.nlm.nih.gov/pubmed/36819922
http://dx.doi.org/10.3389/fgene.2022.900595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930898/
https://www.ncbi.nlm.nih.gov/pubmed/36819922
http://dx.doi.org/10.3389/fgene.2022.900595

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