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Aspirin Restores Radiosensitivity in Cervical Cancer Cells by Inducing Mitotic Catastrophe through Downregulating G2/M Effectors

BACKGROUND/AIM: Compromised cell-cycle checkpoint is a major obstacle for rendering radiotherapeutic success of radioresistant cells. Aspirin (ASA), an anti-inflammatory agent was repurposed previously for improving radiotherapy by limiting radiation toxicity. However, the underlying mechanism was u...

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Detalles Bibliográficos
Autores principales: Das, Salini, Ray, Dilip Kumar, Sengupta, Debomita, Mahapatra, Elizabeth, Biswas, Souvick, Roy, Madhumita, Mukherjee, Sutapa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930979/
https://www.ncbi.nlm.nih.gov/pubmed/36444593
http://dx.doi.org/10.31557/APJCP.2022.23.11.3801