A substructure-based screening approach to uncover N-nitrosamines in drug substances

Drug substances are at risk of contamination with N-nitrosamines (NAs), well-known carcinogenic agents, during synthesis processes and/or long-term storage. Therefore, in this study, we developed an efficient data-based screening approach to systemically assess marketed products and investigated its...

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Detalles Bibliográficos
Autores principales: Kao, Yu-Ting, Wang, Shu-Fen, Wu, Meng-Hsiu, Her, Shwu-Huey, Yang, Yi-Hsuan, Lee, Chung-Hsien, Lee, Hsiao-Feng, Lee, An-Rong, Chang, Li-Chien, Pao, Li-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931005/
https://www.ncbi.nlm.nih.gov/pubmed/35647726
http://dx.doi.org/10.38212/2224-6614.3400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931005/
https://www.ncbi.nlm.nih.gov/pubmed/35647726
http://dx.doi.org/10.38212/2224-6614.3400

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