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Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells

The COVID-19 pandemic has revealed the vulnerability of the modern, global society. With expected waves of future infections by SARS-CoV-2, treatment options for infected individuals will be crucial in order to decrease mortality and hospitalizations. The SARS-CoV-2 main protease is a validated drug...

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Detalles Bibliográficos
Autores principales: Vanhoutte, Roeland, Barniol-Xicota, Marta, Chiu, Winston, Vangeel, Laura, Jochmans, Dirk, De Jonghe, Steven, Zidane, Hadeer, Barr, Haim M., London, Nir, Neyts, Johan, Verhelst, Steven H. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931053/
https://www.ncbi.nlm.nih.gov/pubmed/36819852
http://dx.doi.org/10.1039/d2sc04147b