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Mathematical modeling of pneumococcal transmission dynamics in response to PCV13 infant vaccination in Germany predicts increasing IPD burden due to serotypes included in next-generation PCVs

INTRODUCTION: Two next-generation pneumococcal conjugate vaccines (PCVs), a 15- and a 20-valent PCV (PCV15 and PCV20), have recently been licensed for use in adults, and PCV15 has also been licensed in children. We developed a dynamic transmission model specific for Germany, with the aim to predict...

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Detalles Bibliográficos
Autores principales: Horn, Matthias, Theilacker, Christian, Sprenger, Ralf, von Eiff, Christof, Mahar, Ernestine, Schiffner-Rohe, Julia, Pletz, Mathias W., van der Linden, Mark, Scholz, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931105/
https://www.ncbi.nlm.nih.gov/pubmed/36791091
http://dx.doi.org/10.1371/journal.pone.0281261