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Risk HLA Variants Affect the T-Cell Repertoire in Multiple Sclerosis

BACKGROUND AND OBJECTIVES: The major histocompatibility complex (MHC) locus has a predominant role in the genetic predisposition to multiple sclerosis (MS), with 32 associations found to be involved. We aimed to investigate the impact of MHC MS-risk alleles on T-cell repertoire in patients with MS....

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Detalles Bibliográficos
Autores principales: Sorosina, Melissa, Santoro, Silvia, Ferrè, Laura, Mascia, Elisabetta, Clarelli, Ferdinando, Giordano, Antonino, Cannizzaro, Miryam, Lucia, Moiola, Martinelli, Vittorio, Filippi, Massimo, Esposito, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931183/
https://www.ncbi.nlm.nih.gov/pubmed/36792371
http://dx.doi.org/10.1212/NXI.0000000000200093