Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation

The assembly of the autophagy initiation machinery nucleates autophagosome biogenesis, including in the PINK1- and Parkin-dependent mitophagy pathway implicated in Parkinson’s disease. The structural interaction between the sole transmembrane autophagy protein, autophagy-related protein 9A (ATG9A),...

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Detalles Bibliográficos
Autores principales: Ren, Xuefeng, Nguyen, Thanh N., Lam, Wai Kit, Buffalo, Cosmo Z., Lazarou, Michael, Yokom, Adam L., Hurley, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931213/
https://www.ncbi.nlm.nih.gov/pubmed/36791199
http://dx.doi.org/10.1126/sciadv.adg2997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931213/
https://www.ncbi.nlm.nih.gov/pubmed/36791199
http://dx.doi.org/10.1126/sciadv.adg2997

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