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Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation

The assembly of the autophagy initiation machinery nucleates autophagosome biogenesis, including in the PINK1- and Parkin-dependent mitophagy pathway implicated in Parkinson’s disease. The structural interaction between the sole transmembrane autophagy protein, autophagy-related protein 9A (ATG9A),...

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Detalles Bibliográficos
Autores principales:	Ren, Xuefeng, Nguyen, Thanh N., Lam, Wai Kit, Buffalo, Cosmo Z., Lazarou, Michael, Yokom, Adam L., Hurley, James H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931213/ https://www.ncbi.nlm.nih.gov/pubmed/36791199 http://dx.doi.org/10.1126/sciadv.adg2997

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