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Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy in co-cultured cancer cells
Drug metabolism by the microbiome can influence anticancer treatment success. We previously suggested that chemotherapies with antimicrobial activity can select for adaptations in bacterial drug metabolism that can inadvertently influence the host’s chemoresistance. We demonstrated that evolved resi...
Autores principales: | Sayin, Serkan, Rosener, Brittany, Li, Carmen G, Ho, Bao, Ponomarova, Olga, Ward, Doyle V, Walhout, Albertha JM, Mitchell, Amir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931390/ https://www.ncbi.nlm.nih.gov/pubmed/36734518 http://dx.doi.org/10.7554/eLife.83140 |
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